The following text is an excerpt from the excellent book “Cancer Step Out of the Box” by Ty Bollinger. Reproduced here, with his kind permission.
Protocel (Entelev /Cancell )
Entelev was originally conceived and developed by Jim Sheridan of
Michigan, who was a chemist, attorney, and devout Christian. He began working on his formula back in the 1930s and continued perfecting it until the 1990s. Initially, Sheridan called his product by the scientific name KC49. However since he believed that the basic idea of his formula was a gift from God, Sheridan eventually renamed his formula “Entelev,” which was taken from the Greek word “entelechy” meaning “ that part of man known only to God .” It was eventually renamed Cancell and is currently resold as Protocel .
In this chapter, I will use the term Protocel to represent the line of products which includes both Entelev and Cancell . Even as a young man, Jim was a devout Christian and constantly prayed for God to direct his steps and give him the ability to use his intellect for the good of all mankind, and even had early aspirations to find a cure for cancer. Little did he know that his prayers would be answered and his dreams would be realized.
A devout Christian, Sheridan credited his formula in part to his advanced studies in chemistry and in part to a dream which he believed came from God. He refused any financial compensation, claiming Entelev was “ a gift from God to all his children .” Mr. Sheridan spent his whole life researching, improving the formula, and trying to bring it to the suffering people of the world. When he could not get his formula approved, he gave the product away for free. Such altruism is rarely seen.
What is it and how does it work? Protocel is the world’s most effective free radical scavenger (antioxidant). It is designed to specifically target anaerobic cells in the body by interfering with the production of ATP energy in all of the cells in your body, which in turn lowers the voltage of each cell by between 10% and 20%. The reason that I say that Protocel targets anaerobic ( i.e., cancer) cells is simple. All the cells of our body have a specific voltage, or electrical charge.
Healthy cells have a very high voltage, while unhealthy (anaerobic) cells have a very low voltage, due to the fact that they produce energy via fermentation. The slight reduction in voltage causes anaerobic cancer cells to shift downward to a point below the minimum that they need to remain intact, thus the cells basically self-destruct and break apart, or “lyse” into harmless proteins. The healthy cells of the body typically have such a high normal voltage that the slight reduction in voltage caused by Protocel does not harm them.
Let’s back up a bit, shall we? The process by which our cells produce and distribute energy is called cellular “respiration” or “metabolism.” Most people think of respiration as breathing, but every living cell in the body is technically involved in respiration, because the term “respiration” also refers to a chemical reaction in a cell which involves oxygen and which provides energy to the cell. Crucial to the respiratory system of each cell in our body is a process called “reduction oxidation,” also referred to as the “redox” system.
According to Jim Sheridan, “ This system can be thought of as a ladder, with a different chemical reaction taking place on each step…the bottom steps of the ladder involve relatively simple or ‘primitive’ respiratory reactions. The primitive reactions at the bottom of the ladder take place without oxygen being present. The higher respiratory reactions require the presence of oxygen. Generally, for reduction you move down the ladder. For oxidation you move up the ladder .”
The scientific basis for Protocel is to place a long-term drain of power on cancer cells. Now, cells undergo short-term drains of power all the time. Back in the 1990s, I was a competitive bodybuilder. Working out with weights causes short-term drains of power to the cells, then the cells nicely recover. But when a cell undergoes a long-term drain of power, despite the fact that the cell is overloaded, respiration will continue, but the balance of the respiration system will eventually be affected. For instance, smoking cigarettes causes a long-term drain of power to the cells in the lungs. This type of condition is called a chronic condition in which the cells work constantly and never rest.
A long-term drain of power causes the cell to move slowly down the rungs of the respiratory ladder. As long as there is a drain of power, the cell’s movement down the ladder slowly continues. However, when it reaches a point, which is about 85% of the way down from the top of the ladder, the cell does not fall any further down the ladder and the cell remains “in balance.” This is the lowest the cell can go on the respiratory ladder and still have significant similarities to a normal cell and is also the highest point on the ladder that the cell has similarities to a primitive cell. Sheridan called this point the “critical point” of the respiratory ladder.
The critical point is the dividing line between differentiated (normal) cells and primitive cells and is the point at which a cell turns cancerous. Once pushed down to the critical point, the cell wants to stay in that new steady state at the 15% point on the ladder. The problem with having a cell in steady state at the critical point is that the body doesn’t really recognize the cell, thus it does not know how to deal with it. If the cell were still healthy, it would know how to recharge itself. If the cell were further down the ladder, the body would know how to get rid of it through natural processes. But the cancer cell is walking the line, straddling the fence between normal cells and primitive cells.
One of the chemicals which reduce respiration is catechol. The natural catechols have many different oxidation reduction potentials. Protocel was designed to take advantage of the fact that the cancer cell is “ straddling the fence ” by acting like a catechol, inhibiting respiration at the critical point and effectively forcing the cell to move further down the respiration ladder; so it is completely into the primitive stage. Once the cell is entirely in the primitive stage, the body recognizes it and will attack and dispose of it naturally. In some places (like the brain) the body will form a crust like membrane around the primitive cells. There will be the tumour but it is dead and enclosed. In other places (skin cancer) the body will effectively digest it in a process called lysis (self-digestion).
But won’t a decrease in cellular respiration also damage normal cells? Plain and simply, the answer is “ no .” Remember, normal cells are working well within their potential to produce energy as they are near the top of the respiration ladder. Since normal cells work at such a high level of the redox system, if their respiration potential is reduced somewhat, it is no real problem for them.
According to James Sheridan, “ No special diet is required … However, do not take mega doses of vitamins C and E while taking Entelev/Cancell. The chemical make up of these two vitamins shifts the point on the Oxidation-Reduction ladder where Entelev/Cancell works. Since Entelev/Cancell was designed to hit hardest at the ‘critical point,’ any shift will reduce the effectiveness of Entelev/Cancell .” http://alternativecancer.us/how.htm#diet
Based upon the fact that this protocol’s success hinges upon pushing cancer cells further down the respiration ladder, it is clear that you should not use this protocol in conjunction with products that are intended to increase the production of cellular energy.
Products to avoid include co-enzyme Q10, selenium, alpha lipoic acid, creatine, IGF, spirulina, chlorella, and super algae.
Remember : If you choose this treatment, you must follow the guidelines of which supplements, foods, and other alternative treatments you can combine with Protocel . Many people report noticeable results in three to five weeks. In about two months, most people see results. I have heard it said that Protocel does not actually “kill” the cancer cell per se, but rather enables the body to rid itself of the cancer cells via normal means such as lysis. However, after a long conversation with Tanya Harter Pierce, I believe that Protocel actually does kill the cancer cells. Regardless of the exact cancer cure mechanism, be patient, as this can take a while.
According to Webster Kehr, “ If the Protocel treatment becomes less effective over time, there are a couple of possible reasons. First, is there something you are eating (including supplements) or drinking that is interfering with Protocel? Check this very, very carefully … Second, there may be a more complex problem. The reason Protocel may become less effective is because Protocel may not be able to kill the Multiple-Drug Resistant (MDR) cancer cells (especially if the patient has been on chemotherapy). If you think this is the reason you should immediately add Paw Paw to your treatment. The Paw Paw will not only kill MDR cells, it will also enhance the effectiveness of Protocel in other ways .”
In the 1970s, the NCI started funding Dr. Jerry McLaughlin at Purdue University to find botanical substances that had cytotoxic (cancer killing) potential. He tested and screened over 3,500 species of plants, and found that the acetogenin compounds of the Annonaceae family had the most potential. It is these acetogenins that he found to drastically reduce the ATP production of the cells’ mitochondria. He worked with the various species of this family, including the Paw Paw and Graviola. Using some very sophisticated chemical modeling techniques, he found and isolated over 50 acetogenins in Paw Paw and 28 in Graviola.
These acetogenins, which are basically long chains of carbon atoms, effectively reduce the growth of blood vessels that nourish cancer cells and also inhibit the growth of MDR cells. Both Paw Paw and Graviola can be used to enhance the effectiveness of Protocel as they both block ATP production, thus reducing the voltage of the cell until it basically falls apart via apoptosis. However, according to Dr. McLaughlin, Paw Paw is much more effective than Graviola. Tests were done under the direction of Dr. McLaughlin on two leading Graviola products, and these test showed that Paw Paw had between 24 and 50 times the cytotoxic potency of Graviola.
The combination of Paw Paw or Graviola with Protocel is a powerful “cancer-fighting” cocktail. In order to maximize the effectiveness of this cocktail, they should be taken every six hours, on the hour, twenty-four hours a day, seven days a week. As I mentioned earlier in this chapter, It has been theorized that Paw Paw and Graviola (like Protocel ), were not as effective if they were combined with certain antioxidants. Currently, it is still up for debate.
To be safe, it is recommended that you not take vitamin C and vitamin E with these products, since these two antioxidants do increase ATP and would thus negate their effectiveness. In 1997, Purdue University reported that Graviola’s acetogenins “not only are effective in killing tumors that have proven resistant to anti-cancer agents, but also seem to have a special affinity for such resistant cells.”
It’s important to note that Protocel is a trademarked name for theformulas. Protocel 23 is the trademarked name for Entelev , and Protocel 50 is the trade name for Cancell . The name Protocel was developed shortly before Mr. Sheridan’s death.
I must give credit to Tanya Harter Pierce for her amazing research on Protocel . Much of the information in this chapter comes directly from her research, phone conversations, and emails. I cannot say enough good things about her book Outsmart Your Cancer . It was an excellent source of information on the Protocel treatment protocol. If you choose to use Protocel , then you must purchase her book. It is “required reading” and is available at the following website: www.outsmartyourcancer.com .