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I. P. T. (Insulin Potentiation Therapy


The following text is an excerpt from the excellent book “Cancer Step Out of the Box” by Ty Bollinger.  Reproduced here, with his kind permission.

Although I am opposed to traditional “high dose” chemotherapy, the IPT protocol does involve chemotherapy, albeit in extremely low doses . Over time, traditional chemotherapy dosages compromise the patient’s blood counts, immune system, and organ function to such an extent that they preclude further treatment and oftentimes cause organ damage resulting in the patient’s death. However, IPT eliminates the decision between the “lesser of two evils” that cancer patients face when they are diagnosed.

By targeting a low dose of chemotherapy (less than 1/10 of the typical chemo dosage) to the cancer cells, IPT enhances toxicity to the cancer while reducing toxicity to the patient. It is an extremely safe, effective, and relatively inexpensive cancer therapy used successfully for over 60 years.

Readers will recognize insulin as being the hormone used to treat diabetes. Secreted by the pancreas in healthy people, insulin is a powerful hormone with many actions in the human body, a principal one being to manage the delivery of glucose across cell membranes into cells. Insulin communicates its messages to cells by joining up with specific insulin receptors scattered on the outer surface of the cell membranes. Every cell in the human body has between 100 and 100,000 insulin receptors. Insulin actually opens the cell membrane or “door” to the cell, thereby allowing sugar and other substances to be transported inside. That’s why diabetics, who are unable to produce insulin properly, cannot admit sugar into their cells; thus, they develop hyperglycemia (high blood sugar).

What does this have to do with cancer? It is a well-known scientific fact that cancer cells have an insatiable appetite for glucose. Remember, cancer loves sugar ! Also, remember that cancer cells are an aerobic. So, they produce energy via fermenting glucose, an extremely inefficient way to produce energy, and also one of the reasons that cancer patients lose so much weight. Their cancer cells require so much glucose that they literally steal it away from the body’s normal cells, thus starving the cancer patient.

With IPT, insulin acts as a “potentiator,” tricking the cancer cells into believing they are going to be fed sugar (which they thrive on) when, in fact, they are going to be destroyed by chemotherapy. Since insulin acts as a potentiator and increases the effectiveness of the chemo, far less chemo is needed than with traditional chemo. This means far less side- effects as well as a much more effective treatment.

The interesting connection between cancer cells and insulin is that recent findings published in the scientific medical literature report that cancer cells actually manufacture and secrete their own insulin.

According to Dr. Stephen Ayre, one of the experts in IPT, “ Cancer cells get their energy by secreting their own insulin, and they stimulate themselves to grow by secreting their own insulin-like growth factor (IGF). These are their mechanisms of malignancy. Insulin and IGF work by attaching to special cell membrane receptors, and these receptors are sixteen times more concentrated on cancer cell membranes than on normal cells. These receptors are the key to IPT. Using insulin in IPT, the end result is that the low dose chemotherapy gets channeled specifically inside the cancer cells, killing them more effectively, and with no chemotherapy side-effects. IPT is ingenious; it kills cancer cells by using the very same mechanisms that cancer cells use to kill people .” www.contemporarymedicine.net/ipt_main.htm

The above quote is very important in understanding the mechanism of IPT therapy. IPT kills the cancer cells … and only the cancer cells. Just as cancer cells have their own independent secretion of insulin, they also have their own independent secretion of IGF to provide them with an unlimited stimulus for growth. And cancer cells have 16 times more receptors for insulin and IGF on their cell membranes. Not only can insulin join up with its own specific receptors on cell membranes, but insulin is also able to join up with the receptors for IGF and to communicate messages about growth to the cell. While it may seem highly undesirable for a cancer therapy to actually promote cancer cell growth, this is in fact a valuable effect of insulin here.

You can always tell when someone is undergoing chemotherapy treatments, because they typically lose their hair and are oftentimes very sick and nauseated. Have you ever wondered why? The reason is simple. The cells of patient’s hair follicles and the cells which line the stomach and intestines have one common denominator: They are rapidly dividing cells . So are cancer cells. Chemotherapy drugs like to attack rapidly dividing cells, indiscriminately. However, in a tumor, not all the cancer cells are in this rapidly dividing stage all at once. The fact of the matter is that they take turns.

So when insulin joins up with the IGF receptors on those cancer cells, it stimulates growth in many of the cells that are not in this growth phase. It literally “turns on” cells and makes them active. Then, the chemotherapy administered, after insulin has been injected, actually targets the cells that are “active” and thus more susceptible to the chemotherapy. The end result, which is a beautiful thing for a cancer patient, is that the insulin renders more of these cells susceptible to chemotherapy attack.

How does it work? Basically, during IPT, a small dose of insulin is given to the patient that opens the cell membranes and induces hypoglycemia (low blood sugar), making the patient dizzy and weak. Remember, as Dr. Ayre stated, cancer cells have 16 times more insulin and IGF receptors than normal cells. By inducing hypoglycemia, we can cause the cancer cells to open their receptors at a rate of 16 to 1, thereby allowing us to selectively target cancer cells! It typically takes about half an hour to induce hypoglycemia. Then, the cancer cells think they are going to be fed some sugar and open up their cell “doors.” However, at this point, we pull the “bait and switch” on the cancer cells, as low doses of traditional chemotherapy are administered intravenously. The cancer cells gobble up the chemotherapy, thinking it is sugar, and are killed via much lower doses than typical chemo. In an article appearing in the European Journal of Cancer and Clinical Oncology (Vol. 17, 1981), Dr. Oliver Alabaster of the Cancer Research Laboratory at George Washington University showed that insulin could increase the effectiveness of a certain chemotherapy agent (methotrexate) by as much as 10,000 times and therefore could produce significantly greater results against cancer.

But what would happen if we add DMSO to the IPT equation? According to Dr. Ross Hauser, MD, “ Most medications do not adequately pass the blood-brain barrier. The blood-brain barrier retards the entry of many compounds into the brain, including chemotherapeutic agents. Theoretically, if there was a way to increase the transport of substances into the central nervous system and through the barrier, the efficacy of treatment would be greatly enhanced. ” ( Treating Cancer With Insulin Potentiation Therapy , p. 84) On his website www.caringmedical.com , Dr. Hauser also states, “ Various substances can be used to optimize the cancer-killing effects of chemotherapy, in addition to insulin, dimethyl sulfoxide (DMSO). ” What Dr. Hauser is saying is that the DMSO binds to some types of chemotherapy, and then insulin opens up the membranes of the cancer cells to the chemotherapy. DMSO/IPT is a potent “double whammy” combination of treatments, especially for brain cancer. While combining DMSO with IPT cannot be done at home, it is possible to find an IPT clinic and convince them to combine DMSO with IPT. In Dr. Hauser’s book, he lists the types of chemotherapy drugs that bind to DMSO. This treatment should be extremely potent and have no side effects, since virtually all of the chemo drugs will wind up inside the cancer cells.

IPT has virtually no side effects . There is certainly no hair loss, no going home to shiver in bed for a couple of days, and no severe vomiting. Occasionally, some nausea is encountered for a few hours after the first couple of treatments, but this is also easily managed. IPT is tough against tumors while being very gentle for the patient, who continues to live a normal, vital lifestyle while being treated. Treatments last a little over an hour, so most patients are able to continue to work at their customary vocations while undergoing these weekly treatments. But why doesn’t your doctor know about this effective, less expensive, less damaging protocol? The answer is simple: The FDA hasn’t approved it, except as an “experimental procedure.”

Why doesn’t your oncologist know about this if it has been around for 60 years? It’s not because it hasn’t been documented to Big Medicine and Big Pharma – there are numerous published studies in professional journals. But remember, if you are ever in doubt, just follow the money trail . Let’s put on our “math hats” here and figure out which treatment is more lucrative – traditional chemo or IPT. Well, since IPT uses only 1/10 of the expensive chemo drugs, I guess we found our answer, didn’t we?

A conventional cancer patient on traditional chemotherapy will produce hundreds of thousands of dollars of revenue for the Cancer Industry. Such a simple and effective treatment like IPT would severely cut into their profits, wouldn’t it? Sadly, as we have seen over and over, profits take precedence over principle . As a result, IPT is still being ignored as a much more effective cancer treatment alternative to traditional chemotherapy.

IPT has been in existence as a therapy since 1930, and has been used successfully as a treatment for cancer since January of 1946. IPT was initially developed in 1930 for the treatment of chronic degenerative disease by Donato Perez Garcia, Sr., MD. Over the years, his son (Donato Perez Garcia II, MD) and his grandson (Donato Perez Garcia III, MD) continued using this therapy successfully for several thousands of patients. Dr. Donato Perez III, who trademarked the current name of this treatment, IPTLD® (Insulin Potentiation Targeted Low Dose), now runs a clinic in Tijuana, Mexico. You can learn more about Dr. Perez and his clinic at www.iptldmd.com and you can contact him at drdonato3@iptldmd.com .

Another top notch physician who uses IPT is Dr. Richard Linchitz who runs Linchitz Medical Wellness in Long Island, New York. His website is www.linchitzwellness.com . Dr. Frank Shallenberger also uses bio- oxidative therapies and IPT at his clinic in Nevada. His IPT technology is top-of-the-line, and his website is www.antiagingmedicine.com .


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